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PATZ1 antibody (N-Term)

ZNF278 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7465764
  • Target See all PATZ1 (ZNF278) Antibodies
    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
    Binding Specificity
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 22
    • 16
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 18
    • 4
    Rabbit
    Clonality
    • 20
    • 2
    Polyclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PATZ1 antibody is un-conjugated
    Application
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the N-terminus region of human PATZ1. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product ZNF278 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: HCT116

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.72 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    PATZ1 (ZNF278) (Zinc Finger Protein 278 (ZNF278))
    Alternative Name
    POZ/BTB and AT hook containing zinc finger 1 (ZNF278 Products)
    Synonyms
    ZNF278 antibody, MAZR antibody, PATZ antibody, RIAZ antibody, ZBTB19 antibody, ZSG antibody, dJ400N23 antibody, 8430401L15Rik antibody, AI447519 antibody, Mazr antibody, Patz antibody, Zfp278 antibody, Znf278 antibody, POZ/BTB and AT hook containing zinc finger 1 antibody, POZ/BTB and AT hook containing zinc finger 1 S homeolog antibody, POZ (BTB) and AT hook containing zinc finger 1 antibody, POZ-, AT hook-, and zinc finger-containing protein 1 antibody, PATZ1 antibody, patz1.S antibody, Patz1 antibody, LOC100153931 antibody
    Background
    POZ/BTB and AT hook containing zinc finger 1 , MAZR , PATZ , RIAZ , ZBTB19 , ZNF278 , ZSG , dJ400N23,The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1,22)(p36.1,q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq]
    Molecular Weight
    74 kDa
    Gene ID
    23598
    UniProt
    Q9HBE1
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