CKMT1A antibody

Catalog No. ABIN7465720

Product Details anti-CKMT1A Antibody

Target: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CKMT1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Creatine kinase MT. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299 , HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CKMT1A

Target: CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))

Alternative Name: creatine kinase, mitochondrial 1A (CKMT1A Products)

Synonyms: CKMT1 antibody, Mt-CK antibody, ScCKmit antibody, UbCKmit antibody, mi-CK antibody, Ckmt1 antibody, CKMT1B antibody, Mia-CK antibody, U-MtCK antibody, creatine kinase, mitochondrial 1A antibody, creatine kinase U-type, mitochondrial-like antibody, creatine kinase, mitochondrial 1, ubiquitous antibody, creatine kinase U-type, mitochondrial antibody, CKMT1A antibody, LOC100228000 antibody, Ckmt1 antibody, LOC100725326 antibody

Background: Creatine kinase, mitochondrial 1A , CKMT1 , U-MtCK , mia-CK,Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq]

Molecular Weight: 47 kDa

Gene ID: 548596

UniProt: P12532