NFKBIL2 antibody (N-Term)

Catalog No. ABIN7465712

Product Details anti-NFKBIL2 Antibody

Target: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFKBIL2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human NFKBIL2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299 , HCT116 , MCF-7

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.81 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NFKBIL2

Target: NFKBIL2 (Tonsoku-Like, DNA Repair Protein (NFKBIL2))

Alternative Name: tonsoku like, DNA repair protein (NFKBIL2 Products)

Synonyms: IKBR antibody, NFKBIL2 antibody, 2810439M11Rik antibody, Nfkbil2 antibody, im:7145273 antibody, nfkbil2 antibody, tonsl antibody, tonsoku like, DNA repair protein antibody, tonsoku-like, DNA repair protein antibody, TONSL antibody, Tonsl antibody, tonsl antibody

Background: Tonsoku like, DNA repair protein , IKBR , NFKBIL2,The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus. [provided by RefSeq]

Molecular Weight: 151 kDa

Gene ID: 4796

UniProt: Q96HA7

Pathways: Maintenance of Protein Location