RGS11 antibody

Catalog No. ABIN7465689

Product Details anti-RGS11 Antibody

Target: RGS11 (Regulator of G-Protein Signaling 11 (RGS11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS11 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human RGS11. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: H1299

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RGS11

Target: RGS11 (Regulator of G-Protein Signaling 11 (RGS11))

Alternative Name: regulator of G protein signaling 11 (RGS11 Products)

Synonyms: RS11 antibody, C78048 antibody, XRGSIV antibody, rgs9-a antibody, regulator of G protein signaling 11 antibody, regulator of G-protein signaling 11 antibody, regulator of G-protein signaling 11 L homeolog antibody, RGS11 antibody, Rgs11 antibody, rgs11.L antibody

Background: Regulator of G protein signaling 11 , RS11,The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq]

Molecular Weight: 53 kDa

Gene ID: 8786

UniProt: O94810

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling