DNASE2B antibody

Catalog No. ABIN7465547

Product Details anti-DNASE2B Antibody

Target: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNASE2B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DNASE2B. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.91 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DNASE2B

Target: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Alternative Name: deoxyribonuclease 2 beta (DNASE2B Products)

Synonyms: DNASE2 antibody, deoxyribonuclease-2-beta antibody, DLAD antibody, DNASE2B antibody, dnase2b antibody, AI526873 antibody, Dlad antibody, DnaseIIb antibody, UOX antibody, deoxyribonuclease 2 beta antibody, deoxyribonuclease II beta antibody, DNASE2B antibody, dnase2b antibody, Dnase2b antibody

Background: Deoxyribonuclease 2 beta , DLAD,The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]

Molecular Weight: 42 kDa

Gene ID: 58511

UniProt: Q8WZ79