DCPS antibody

Catalog No. ABIN7465524

Product Details anti-DCPS Antibody

Target: DCPS (Decapping Enzyme, Scavenger (DCPS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCPS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DCPS. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A549

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DCPS

Target: DCPS (Decapping Enzyme, Scavenger (DCPS))

Alternative Name: decapping enzyme, scavenger (DCPS Products)

Synonyms: DCPS antibody, DCS1 antibody, HINT-5 antibody, HINT5 antibody, HSL1 antibody, 1700001E16Rik antibody, AA408441 antibody, Hint-5 antibody, decapping enzyme, scavenger antibody, DCPS antibody, dcps antibody, Dcps antibody

Background: Decapping enzyme, scavenger , ARS , DCS1 , HINT-5 , HINT5 , HSL1 , HSPC015,Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.

Molecular Weight: 39 kDa

Gene ID: 28960

UniProt: Q96C86