MED16 antibody
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- Target See all MED16 Antibodies
- MED16 (Mediator Complex Subunit 16 (MED16))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MED16 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human THRAP5. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product MED16 Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: A431 , HeLa , HepG2
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- MED16 (Mediator Complex Subunit 16 (MED16))
- Alternative Name
- mediator complex subunit 16 (MED16 Products)
- Synonyms
- THRAP5 antibody, MED16 antibody, DRIP92 antibody, TRAP95 antibody, 95kDa antibody, A630083L04 antibody, Thrap5 antibody, Trap95 antibody, mediator complex subunit 16 antibody, mediator complex subunit 16 L homeolog antibody, MED16 antibody, Med16 antibody, med16.L antibody
- Background
- Mediator complex subunit 16 , DRIP92 , THRAP5 , TRAP95,Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
- Molecular Weight
- 97 kDa
- Gene ID
- 10025
- UniProt
- Q9Y2X0
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha
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