NMT1 antibody (N-Term)

Catalog No. ABIN7465185

Product Details anti-NMT1 Antibody

Target: NMT1 (N-Myristoyltransferase 1 (NMT1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human NMT1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.42 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for NMT1

Target: NMT1 (N-Myristoyltransferase 1 (NMT1))

Alternative Name: N-myristoyltransferase 1 (NMT1 Products)

Synonyms: NMT antibody, im:2601337 antibody, nmt1 antibody, wu:fc15d01 antibody, wu:fc18a04 antibody, zgc:110714 antibody, MGC145283 antibody, AW536594 antibody, ARABIDOPSIS THALIANA MYRISTOYL-COA:PROTEIN N-MYRISTOYLTRANSFERASE antibody, ATNMT1 antibody, MHM17.15 antibody, MHM17_15 antibody, N-MYRISTOYLTRANSFERASE 1 antibody, myristoyl-CoA:protein N-myristoyltransferase antibody, N-myristoyltransferase 1 antibody, N-myristoyltransferase 1a antibody, N-myristoyltransferase 1 L homeolog antibody, N-myristoyltransferase 1 (predicted) antibody, myristoyl-CoA:protein N-myristoyltransferase antibody, NMT1 antibody, nmt1a antibody, nmt1.L antibody, nmt1 antibody, SPBC2G2.11 antibody, Nmt1 antibody

Background: N-myristoyltransferase 1 , NMT,Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT, EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1, MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM]

Molecular Weight: 57 kDa

Gene ID: 4836

UniProt: P30419

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling