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PHF2 antibody

PHF2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7465155
  • Target See all PHF2 Antibodies
    PHF2 (PHD Finger Protein 2 (PHF2))
    Reactivity
    • 14
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 13
    • 2
    Rabbit
    Clonality
    • 13
    • 2
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHF2 antibody is un-conjugated
    Application
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human PHF2. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product PHF2 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: 293T , A431 , HeLa , HepG2

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    PHF2 (PHD Finger Protein 2 (PHF2))
    Alternative Name
    PHD finger protein 2 (PHF2 Products)
    Synonyms
    CENP-35 antibody, GRC5 antibody, JHDM1E antibody, im:4200679 antibody, phf8 antibody, wu:fa14c10 antibody, PHD finger protein 2 antibody, PHF2 antibody, Phf2 antibody, phf2 antibody
    Background
    PHD finger protein 2 , CENP-35 , GRC5 , JHDM1E , KDM7C,Probable regulator of histone methyltransferase complexes. Recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA. Was reported to have histone demethylase activity by itself and specifically demethylate monomethylated 'Lys-9' of histone H3 (H3K9me1), an epigenetic repressive mark. However, this activity is unclear in vivo and requires additional evidence.
    Molecular Weight
    121 kDa
    Gene ID
    5253
    UniProt
    O75151
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