SGCG antibody

Catalog No. ABIN7464807

Product Details anti-SGCG Antibody

Target: SGCG (Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGCG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human gamma Sarcoglycan. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse muscle , rat muscle

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SGCG

Target: SGCG (Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG))

Alternative Name: sarcoglycan gamma (SGCG Products)

Synonyms: zgc:100924 antibody, A4 antibody, DAGA4 antibody, DMDA antibody, DMDA1 antibody, LGMD2C antibody, MAM antibody, SCARMD2 antibody, SCG3 antibody, TYPE antibody, 35DAG antibody, Gamma-SG antibody, 35kDa antibody, 5430420E18Rik antibody, AI642964 antibody, gamma-SG antibody, sarcoglycan, gamma antibody, sarcoglycan gamma antibody, sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) antibody, sarcoglycan, gamma (dystrophin-associated glycoprotein) antibody, sgcg antibody, SGCG antibody, Sgcg antibody

Background: Sarcoglycan gamma , 35DAG , A4 , DAGA4 , DMDA , DMDA1 , LGMD2C , LGMDR5 , MAM , SCARMD2 , SCG3 , gamma-SG,This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]

Molecular Weight: 32 kDa

Gene ID: 6445

UniProt: Q13326