BIRC2 antibody

Catalog No. ABIN7464662

Product Details anti-BIRC2 Antibody

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BIRC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Purification: Affinity purified by Protein G.

Grade: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the center region of human cIAP1. The exact sequence is proprietary.

Clone: GT422

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat , Raji , NCI-H929 , BIRC2-transfected 293T

Validation: KO/KD, Overexpression

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for BIRC2

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Alternative Name: baculoviral IAP repeat containing 2 (BIRC2 Products)

Synonyms: API1 antibody, HIAP2 antibody, Hiap-2 antibody, MIHB antibody, RNF48 antibody, c-IAP1 antibody, cIAP1 antibody, Api2 antibody, rIAP1 antibody, IAP1 antibody, ITA antibody, AW146227 antibody, Api1 antibody, Birc3 antibody, HIAP1 antibody, IAP2 antibody, MIAP1 antibody, MIAP2 antibody, MIHC antibody, cIAP2 antibody, mcIAP1 antibody, ciap-1 antibody, birc3 antibody, api1 antibody, birc2 antibody, c-iap1 antibody, ciap1 antibody, hiap-2 antibody, hiap2 antibody, mihb antibody, rnf48 antibody, baculoviral IAP repeat containing 2 antibody, baculoviral IAP repeat-containing 2 antibody, baculoviral IAP repeat containing 2 L homeolog antibody, BIRC2 antibody, Birc2 antibody, birc2 antibody, birc2.L antibody

Background: Baculoviral IAP repeat containing 2 , API1 , HIAP2 , Hiap-2 , MIHB , RNF48 , c-IAP1 , cIAP1,The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. [provided by RefSeq]

Molecular Weight: 70 kDa

Gene ID: 329

UniProt: Q13490

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades