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BIRC2 antibody

KO Validated BIRC2 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal GT422 unconjugated
Catalog No. ABIN7464662
  • Target See all BIRC2 Antibodies
    BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
    Reactivity
    • 43
    • 11
    • 5
    Human
    Host
    • 40
    • 3
    Mouse
    Clonality
    • 40
    • 3
    Monoclonal
    Conjugate
    • 17
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIRC2 antibody is un-conjugated
    Application
    • 32
    • 22
    • 21
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human
    Purification
    Affinity purified by Protein G.
    Grade
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human cIAP1. The exact sequence is proprietary.
    Clone
    GT422
    Isotype
    IgG2a
    Top Product
    Discover our top product BIRC2 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: Jurkat , Raji , NCI-H929 , BIRC2-transfected 293T

    Validation: KO/KD, Overexpression

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, No Preservative
    Preservative
    Without preservative
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
    Alternative Name
    baculoviral IAP repeat containing 2 (BIRC2 Products)
    Synonyms
    API1 antibody, HIAP2 antibody, Hiap-2 antibody, MIHB antibody, RNF48 antibody, c-IAP1 antibody, cIAP1 antibody, Api2 antibody, rIAP1 antibody, IAP1 antibody, ITA antibody, AW146227 antibody, Api1 antibody, Birc3 antibody, HIAP1 antibody, IAP2 antibody, MIAP1 antibody, MIAP2 antibody, MIHC antibody, cIAP2 antibody, mcIAP1 antibody, ciap-1 antibody, birc3 antibody, api1 antibody, birc2 antibody, c-iap1 antibody, ciap1 antibody, hiap-2 antibody, hiap2 antibody, mihb antibody, rnf48 antibody, baculoviral IAP repeat containing 2 antibody, baculoviral IAP repeat-containing 2 antibody, baculoviral IAP repeat containing 2 L homeolog antibody, BIRC2 antibody, Birc2 antibody, birc2 antibody, birc2.L antibody
    Background
    Baculoviral IAP repeat containing 2 , API1 , HIAP2 , Hiap-2 , MIHB , RNF48 , c-IAP1 , cIAP1,The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. [provided by RefSeq]
    Molecular Weight
    70 kDa
    Gene ID
    329
    UniProt
    Q13490
    Pathways
    Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
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