CHD1L antibody
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- Target See all CHD1L Antibodies
- CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHD1L antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Cross-Reactivity
- Human
- Purification
- Purified by antigen-affinity chromatography.
- Grade
- KO Validated
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human CHD1L. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product CHD1L Primary Antibody
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- Application Notes
- WB: 1:1000-1:10000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: HepG2 nucleus , 293T
Validation: KO/KD
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.02 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CHD1L (Chromodomain Helicase DNA Binding Protein 1-Like (CHD1L))
- Alternative Name
- chromodomain helicase DNA binding protein 1 like (CHD1L Products)
- Synonyms
- CHD1L antibody, ALC1 antibody, CHDL antibody, 4432404A22Rik antibody, Alc1 antibody, Snf2p antibody, zgc:56084 antibody, chromodomain helicase DNA binding protein 1 like antibody, chromodomain helicase DNA binding protein 1-like antibody, CHD1L antibody, chd1l antibody, Chd1l antibody
- Background
- Chromodomain helicase DNA binding protein 1 like , ALC1 , CHDL,In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1, MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM]
- Molecular Weight
- 101 kDa
- Gene ID
- 9557
- UniProt
- Q86WJ1
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