RNASEH2B antibody

Catalog No. ABIN7464457

Product Details anti-RNASEH2B Antibody

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RNASEH2B antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Affinity purified by Protein G.

Immunogen: Recombinant protein encompassing a sequence within the center region of human RNaseH2B. The exact sequence is proprietary.

Clone: GT673

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa , HeLa nuclear extract

Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.01 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RNASEH2B

Target: RNASEH2B (Ribonuclease H2, Subunit B (RNASEH2B))

Alternative Name: ribonuclease H2 subunit B (RNASEH2B Products)

Synonyms: AGS2 antibody, DLEU8 antibody, 1110019N06Rik antibody, 2610207P08Rik antibody, Dleu8 antibody, ribonuclease H2 subunit B antibody, ribonuclease H2, subunit B antibody, ribonuclease H2 subunit B L homeolog antibody, RNASEH2B antibody, Rnaseh2b antibody, rnaseh2b.L antibody

Background: Ribonuclease H2 subunit B , AGS2 , DLEU8,RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq]

Molecular Weight: 35 kDa

Gene ID: 79621

UniProt: Q5TBB1