RNPS1 antibody (N-Term)

Catalog No. ABIN7464180

Product Details anti-RNPS1 Antibody

Target: RNPS1 (RNA-Binding Protein S1 (RNPS1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNPS1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Grade: KO Validated

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human RNPS1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for RNPS1

Target: RNPS1 (RNA-Binding Protein S1 (RNPS1))

Alternative Name: RNA binding protein with serine rich domain 1 (RNPS1 Products)

Synonyms: E5.1 antibody, ribonucleic acid binding protein S1 antibody, RNA binding protein with serine rich domain 1 antibody, RNA binding protein S1, serine-rich domain antibody, Rnps1 antibody, RNPS1 antibody

Background: RNA binding protein with serine rich domain 1 , E5.1,This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splice variants have been found for this gene, both variants encode the same protein. [provided by RefSeq]

Molecular Weight: 34 kDa

Gene ID: 10921

UniProt: Q15287