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Sca-1/Ly-6A/E antibody (FITC)

Ly6a Reactivity: Mouse FACS Host: Rat Monoclonal D7 FITC
Catalog No. ABIN7456879
  • Target See all Sca-1/Ly-6A/E (Ly6a) Antibodies
    Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))
    Reactivity
    • 51
    • 6
    • 1
    Mouse
    Host
    • 31
    • 25
    Rat
    Clonality
    • 37
    • 17
    Monoclonal
    Conjugate
    • 13
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Sca-1/Ly-6A/E antibody is conjugated to FITC
    Application
    • 31
    • 14
    • 11
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Clone
    D7
    Isotype
    IgG2a, kappa
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    Discover our top product Ly6a Primary Antibody
  • Application Notes
    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
    Comment

    Matching Isotype Control: FITC Rat IgG2a, κ Isotype Control (ABIN7469839)

    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % Proclin300, 1 % BSA
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • Target
    Sca-1/Ly-6A/E (Ly6a) (Lymphocyte Antigen 6 Complex, Locus A (Ly6a))
    Alternative Name
    Ly6A/E(Sca-1) (Ly6a Products)
    Synonyms
    Ly-6A.2 antibody, Ly-6A/E antibody, Ly-6E.1 antibody, Sca-1 antibody, Sca1 antibody, TAP antibody, lymphocyte antigen 6 complex, locus A antibody, Ly6a antibody
    Background
    Ly6a,Ly6,Ly-6A.2/Ly-6E.1,SCA-1,TAP,Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
    Gene ID
    110454
    UniProt
    P05533
    Pathways
    Sensory Perception of Sound, Activated T Cell Proliferation
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