RCOR3 antibody (AA 445-495)

Catalog No. ABIN7455241

Product Details anti-RCOR3 Antibody

Target: RCOR3 (REST Corepressor 3 (RCOR3))

Binding Specificity: AA 445-495

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCOR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (fixed cells) (IF/ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-RCOR3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 445 and 495

Isotype: IgG

Application Details

Application Notes:

ICC-IF: 1:50 - 1:250.

IHC-IF: 1:100 - 1:500

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RCOR3

Target: RCOR3 (REST Corepressor 3 (RCOR3))

Alternative Name: RCOR3 (RCOR3 Products)

Synonyms: RCOR3 antibody, si:ch211-284e20.6 antibody, RP11-318L16.1 antibody, 4921514E24Rik antibody, C730034D20Rik antibody, E130101E15Rik antibody, REST corepressor 3 antibody, REST corepressor 3 S homeolog antibody, REST corepressor 3-like antibody, RCOR3 antibody, rcor3 antibody, Tsp_00093 antibody, rcor3.S antibody, Rcor3 antibody, LOC100510922 antibody

Background: Background: RCOR3 is a member of the coREST family that functions as a co-repressor for REST (RE1-silencing transcription factor) to regulate neuronal gene expression and neuronal stem cell fate. The coREST family includes RCOR1, also known as coREST, RCOR2, and RCOR3. REST complexes regulate gene expression by modifying chromatin to create a repressive epigenetic environment.

Gene ID: 55758

NCBI Accession: NP_060724

UniProt: Q9P2K3

Pathways: Chromatin Binding