PRPF8 antibody (AA 1825-1875)

Catalog No. ABIN7454982

Product Details anti-PRPF8 Antibody

Target: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Binding Specificity: AA 1825-1875

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRPF8 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-PRPF8 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1825 and 1875

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PRPF8

Target: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Alternative Name: PRPF8 (PRPF8 Products)

Background: Background: Pre-mRNA-processing-splicing factor 8 (PRPF8) is a central component of the spliceosome, which may play a role in aligning the pre-mRNA 5'- and 3'-exons for ligation. PRPF8 interacts with U5 snRNA, and with pre-mRNA 5'-splice sites in B spliceosomes and 3'-splice sites in C spliceosomes [taken from the Universal Protein Resource (UniProt) Q8TCS8].

Gene ID: 10594

NCBI Accession: NP_006436

UniProt: Q6P2Q9