POLR2C antibody (AA 225-275)
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- Target See all POLR2C Antibodies
- POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))
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Binding Specificity
- AA 225-275
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLR2C antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Purpose
- Rabbit anti-RPB3 Antibody, Affinity Purified
- Predicted Reactivity
- Bovine
- Purification
- Affinity Purified
- Immunogen
- Between AA 225 and 275
- Isotype
- IgG
- Top Product
- Discover our top product POLR2C Primary Antibody
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- Application Notes
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IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- POLR2C (Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C))
- Alternative Name
- RPB3 (POLR2C Products)
- Synonyms
- RPB3 antibody, RPB31 antibody, hRPB33 antibody, hsRPB3 antibody, 33kDa antibody, Rpo2-3 antibody, mRBP31 antibody, zgc:56285 antibody, wu:fk48d01 antibody, MGC76329 antibody, MGC81245 antibody, POLR2C antibody, polr2c antibody, rpb3 antibody, RNA polymerase II subunit C antibody, polymerase (RNA) II (DNA directed) polypeptide C antibody, polymerase (RNA) II (DNA directed) polypeptide C, 33kDa antibody, polymerase (RNA) II (DNA directed) polypeptide C, 33kDa S homeolog antibody, POLR2C antibody, Polr2c antibody, polr2c antibody, polr2c.S antibody
- Background
- Background: RPB3 (RNA polymerase II subunit 3) is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is a component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft [taken from the Universal Protein Resource (UniProt) P19387].
- Gene ID
- 5432
- NCBI Accession
- NP_116558
- UniProt
- P19387
- Pathways
- Regulatory RNA Pathways
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