TRPS1 antibody (AA 1000-1050)

Catalog No. ABIN7454931

Product Details anti-TRPS1 Antibody

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Binding Specificity: AA 1000-1050

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-TRPS1 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 1000 and 1050

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TRPS1

Target: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Alternative Name: TRPS1 (TRPS1 Products)

Synonyms: GC79 antibody, LGCR antibody, AI115454 antibody, AI447310 antibody, D15Ertd586e antibody, transcriptional repressor GATA binding 1 antibody, transcriptional repressor GATA binding 1 S homeolog antibody, Trps1 antibody, TRPS1 antibody, trps1.S antibody

Background: Background: Tricho-rhino-phalangeal syndrome type I protein (TRPS1) is a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of TRPS1 to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in the TRPS1 gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III [taken from NCBI Entrez Gene (Gene ID: 7227)].

Gene ID: 7227

UniProt: Q9UHF7

Pathways: Protein targeting to Nucleus