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PABPN1 antibody (AA 1-50)

PABPN1 Reactivity: Human, Mouse WB, IP, IHC (fp) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7454922
  • Target See all PABPN1 Antibodies
    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
    Binding Specificity
    • 8
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    AA 1-50
    Reactivity
    • 39
    • 19
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Human, Mouse
    Host
    • 39
    Rabbit
    Clonality
    • 30
    • 9
    Polyclonal
    Conjugate
    • 15
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PABPN1 antibody is un-conjugated
    Application
    • 24
    • 13
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    Purpose
    Rabbit anti-PABPN1 Antibody, Affinity Purified
    Predicted Reactivity
    Bovine
    Purification
    Affinity Purified
    Immunogen
    between AA 1 and 50
    Isotype
    IgG
    Top Product
    Discover our top product PABPN1 Primary Antibody
  • Application Notes

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 10 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Expiry Date
    12 months
  • Target
    PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
    Alternative Name
    PABPN1 (PABPN1 Products)
    Synonyms
    OPMD antibody, PAB2 antibody, PABII antibody, PABP-2 antibody, PABP2 antibody, Pabp3 antibody, mPABII antibody, ARABIDOPSIS POLY(A) BINDING 2 antibody, ATPAB2 antibody, F28A23.130 antibody, F28A23_130 antibody, POLY(A) BINDING PROTEIN 2 antibody, POLY(A)-BINDING PROTEIN 2 antibody, poly(A) binding protein 2 antibody, opmd antibody, pab2 antibody, pabp2 antibody, pabpii antibody, pabpn1 antibody, Pabpn1 antibody, Poly(A)-binding protein 2 antibody, fb19c03 antibody, wu:fb17e03 antibody, wu:fb18c06 antibody, wu:fb19c03 antibody, zgc:85979 antibody, zgc:92452 antibody, poly(A) binding protein nuclear 1 antibody, poly(A) binding protein, nuclear 1 antibody, poly(A) binding protein 2 antibody, poly(A) binding protein, nuclear 1 S homeolog antibody, poly(A) binding protein, nuclear 1 L homeolog antibody, polyadenylate-binding protein 2 antibody, poly(A) binding protein Pab2 antibody, PABPN1 antibody, Pabpn1 antibody, PAB2 antibody, pabpn1.S antibody, pabpn1.L antibody, LOC100728725 antibody, pab2 antibody, pabpn1 antibody
    Background
    Background: Polyadenylate binding protein, nuclear 1 (PABPN1) is involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product. PABPN1 stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and also controls the poly(A) tail length. PABPN1 increases the affinity of poly(A) polymerase for RNA and is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA [taken from the Universal Protein Resource (UniProt) Q86U42].
    Gene ID
    8106
    NCBI Accession
    NP_004634
    UniProt
    Q86U42
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