Reticulon 3 antibody (AA 750-800)

Catalog No. ABIN7454878

Product Details anti-Reticulon 3 Antibody

Target: Reticulon 3 (RTN3)

Binding Specificity: AA 750-800

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Reticulon 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-Reticulon-3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 750 and 800

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Reticulon 3

Target: Reticulon 3 (RTN3)

Alternative Name: Reticulon-3 (RTN3 Products)

Synonyms: ASYIP antibody, HAP antibody, NSPL2 antibody, NSPLII antibody, RTN3-A1 antibody, MGC56439 antibody, zgc:56439 antibody, zgc:77630 antibody, RTN3 antibody, hap antibody, asyip antibody, nspl2 antibody, xrtn3 antibody, nsplii antibody, rtn3-a1 antibody, RTN3w antibody, rtn3 antibody, XRTN3 antibody, rtn3-a antibody, rtn3-b antibody, reticulon 3 antibody, reticulon 3 L homeolog antibody, reticulon-3 antibody, reticulon 3 S homeolog antibody, RTN3 antibody, Rtn3 antibody, rtn3 antibody, rnt3 antibody, rtn3.L antibody, LOC107131155 antibody, rtn3.S antibody

Background: Background: Reticulon-3 may be involved in membrane trafficking in the early secretory pathway. Reticulon-3 inhibits BACE1 activity and amyloid precursor protein processing. It may induce caspase-8 cascade and apoptosis and may favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, Reticulon-3 may be involved in the viral replication or pathogenesis [taken from the Universal Protein Resource (UniProt) O95197].

Gene ID: 10313

UniProt: O95197