MED13L antibody (AA 550-600)

Catalog No. ABIN7454828

Product Details anti-MED13L Antibody

Target: MED13L (Mediator Complex Subunit 13-Like (MED13L))

Binding Specificity: AA 550-600

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED13L antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-MED13L Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 550 and 600

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for MED13L

Target: MED13L (Mediator Complex Subunit 13-Like (MED13L))

Alternative Name: MED13L (MED13L Products)

Background: Background: Mediator complex subunit 13-like is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. [taken from the Universal Protein Resource (UniProt) Q71F56].

Gene ID: 23389

NCBI Accession: NP_056150

UniProt: Q71F56

Pathways: Regulation of Lipid Metabolism by PPARalpha