XPA antibody (AA 1-50)
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- Target See all XPA Antibodies
- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
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Binding Specificity
- AA 1-50
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This XPA antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Purpose
- Rabbit anti-XPA Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogen
- Between AA 1 and 50
- Isotype
- IgG
- Top Product
- Discover our top product XPA Primary Antibody
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- Application Notes
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IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
- Alternative Name
- XPA (XPA Products)
- Synonyms
- CG6358 antibody, DhR14 antibody, DhXPA antibody, DmXPA antibody, Dmel\\CG6358 antibody, Dxpa antibody, EG:EG0007.8 antibody, XPAC antibody, XPA_DROME antibody, Xpa antibody, dmXPA antibody, dxpa antibody, XP1 antibody, AI573865 antibody, Xpac antibody, xpac antibody, xxpa antibody, Xeroderma pigmentosum group A-like antibody, XPA, DNA damage recognition and repair factor antibody, xeroderma pigmentosum, complementation group A antibody, xeroderma pigmentosum, complementation group A L homeolog antibody, Xpac antibody, XPA antibody, Xpa antibody, xpa.L antibody
- Background
- Background: Mutations in XPA (xeroderma pigmentosum group A-complementing protein) are the cause of xeroderma pigmentosum A (XP-A), an autosomal recessive disease that is mainly characterized by a susceptibility to UV-induced skin cancer and in some cases neurological abnormalities. XPA is one of seven XP complementation groups that have been identified. The XP complementation groups represent genes critical to the nucleotide excision repair (NER) pathway. XPA is thought to function in the recognition of DNA damage and as a processivity factor for XPF and XPG.
- Gene ID
- 7507
- NCBI Accession
- NP_000371
- UniProt
- P23025
- Pathways
- DNA Damage Repair
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