SCAF11 antibody (C-Term)

Catalog No. ABIN7454710

Product Details anti-SCAF11 Antibody

Target: SCAF11 (SR-Related CTD-Associated Factor 11 (SCAF11))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCAF11 antibody is un-conjugated

Application: Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-SFRS2IP Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1098 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SCAF11

Target: SCAF11 (SR-Related CTD-Associated Factor 11 (SCAF11))

Alternative Name: SFRS2IP (SCAF11 Products)

Synonyms: ICE(rel)II antibody, ICEREL-II antibody, ICH-2 antibody, Mih1/TX antibody, TX antibody, CASP11 antibody, SFRS2IP antibody, SIP1 antibody, SRRP129 antibody, SRSF2IP antibody, 1110061H03Rik antibody, 2610510E10Rik antibody, AI462454 antibody, Sfrs2ip antibody, Srsf2ip antibody, mKIAA3013 antibody, caspase 4 antibody, SR-related CTD associated factor 11 antibody, caspase 11 antibody, SR-related CTD-associated factor 11 antibody, CASP4 antibody, SCAF11 antibody, LOC100101589 antibody, Scaf11 antibody

Background: Background: SFRS2IP was identified as factor that interacts with SC35, an SR family member critical to mRNA splicing. SFRS2IP contains an arginine-serine-rich (RS) domain and lacks any known RNA-binding motifs. SFRS2IP may have an important role in splicesome assembly since it has been demonstrated to interact with several proteins involved in the early steps of splicesome assembly and the finding that splicesomal complexes A and B are not formed in SFRS2IP depleted extracts.

Gene ID: 9169

UniProt: Q99590