DDX20 antibody (AA 600-650)

Catalog No. ABIN7454654

Product Details anti-DDX20 Antibody

Target: DDX20 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (DDX20))

Binding Specificity: AA 600-650

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX20 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-DDX20 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 600 and 650

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 1 - 4 μg/mg lysate

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DDX20

Target: DDX20 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 20 (DDX20))

Alternative Name: DDX20 (DDX20 Products)

Synonyms: DDX20 antibody, DP103 antibody, GEMIN3 antibody, dp103 antibody, Dp103 antibody, si:dkey-193l3.3 antibody, wu:fb16g08 antibody, wu:fb59a11 antibody, DEAD-box helicase 20 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 antibody, DDX20 antibody, ddx20 antibody, Ddx20 antibody

Background: Background: DDX20 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. Some members of the DEAD box proteins also exhibit functions involved in transcriptional regulation. In addition to its role in snRNP assembly, DDX20 can function as a transcriptional repressor.

Gene ID: 11218

NCBI Accession: NP_009135

UniProt: Q9UHI6

Pathways: Ribonucleoprotein Complex Subunit Organization