PYDC1 antibody (AA 1050-1100)

Catalog No. ABIN7454625

Product Details anti-PYDC1 Antibody

Target: PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))

Binding Specificity: AA 1050-1100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYDC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-ASC2 Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: between AA 1050 and 1100

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PYDC1

Target: PYDC1 (PYD (Pyrin Domain) Containing 1 (PYDC1))

Alternative Name: ASC2 (PYDC1 Products)

Synonyms: ASC2 antibody, POP1 antibody, PYC1 antibody, pyrin domain containing 1 antibody, PYDC1 antibody

Background: Background: Activating signal co-integrator 2 (ASC2) functions as a hormone-dependent transcriptional coactivator in cooperation with nuclear receptors such as steroids, retinoids, thyroid hormone, vitamin D3 and prostanoids. ASC2 also interacts with basal transcription factors and may also influence gene expression through its association with histone modifiers. ASC2 has been identified as an amplified gene in breast and other human cancers.

Gene ID: 23054

NCBI Accession: NP_054790

UniProt: Q14686