NRBF2 antibody (AA 125-175)

Catalog No. ABIN7454421

Product Details anti-NRBF2 Antibody

Target: NRBF2 (Nuclear Receptor Binding Factor 2 (NRBF2))

Binding Specificity: AA 125-175

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NRBF2 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-NRBF2 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 125 and 175

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-NRBF2 antibody A301-852A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NRBF2

Target: NRBF2 (Nuclear Receptor Binding Factor 2 (NRBF2))

Alternative Name: NRBF2 (NRBF2 Products)

Synonyms: COPR1 antibody, COPR2 antibody, NRBF-2 antibody, nuclear receptor binding factor 2 antibody, NRBF2 antibody, Nrbf2 antibody

Background: Background: NRBF2 (nuclear receptor binding factor-2) was originally identified in a yeast two-hybrid screen for factors that interact with the peroxisome proliferator-activated receptor alpha (PPARalpha). In a second study, NRBF2 was also identified in a screen of a keratinocyte cDNA library and named COPR (comodulator of PPAR and RXR). In this study, NRBF2 was proposed to function as a modulator of transcriptional activity that functions to decrease rather than completely repress nuclear-receptor mediated gene expression.

Gene ID: 29982

NCBI Accession: NP_110386

UniProt: Q96F24

Pathways: Nuclear Receptor Transcription Pathway