WDR4 antibody (AA 225-275)

Catalog No. ABIN7454411

Product Details anti-WDR4 Antibody

Target: WDR4 (WD Repeat Domain 4 (WDR4))

Binding Specificity: AA 225-275

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR4 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-WDR4 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 225 and 275

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-WDR4 antibody A301-555A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for WDR4

Target: WDR4 (WD Repeat Domain 4 (WDR4))

Alternative Name: WDR4 (WDR4 Products)

Synonyms: TRM82 antibody, TRMT82 antibody, AI415180 antibody, AI448349 antibody, D530049K22Rik antibody, WD repeat domain 4 antibody, WD repeat domain 4 S homeolog antibody, WDR4 antibody, Wdr4 antibody, wdr4.S antibody

Background: Background: WDR4 (WD repeat-containing protein 4) was identified in a search for candidate genes involved in the development of Down syndrome phenotypes. It is required for the 7-methylguanosine (m7G)-methyltransferase activity for tRNA. WDR bears two WD repeats. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation.

Gene ID: 10785

NCBI Accession: NP_061139

UniProt: P57081