ZFP106 antibody (AA 1833-1883)

Catalog No. ABIN7454408

Product Details anti-ZFP106 Antibody

Target: ZFP106 (Zinc Finger Protein 106 Homolog (ZFP106))

Binding Specificity: AA 1833-1883

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFP106 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-ZFP106 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 1833 and 1883

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-ZFP106 antibody A301-526A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ZFP106

Target: ZFP106 (Zinc Finger Protein 106 Homolog (ZFP106))

Alternative Name: ZFP106 (ZFP106 Products)

Synonyms: ZFP106 antibody, DKFZp468J1816 antibody, SH3BP3 antibody, ZNF474 antibody, Cd-1 antibody, D2Dcr28 antibody, H3a antibody, Sh3bp3 antibody, Znf106 antibody, sirm antibody, zinc finger protein 106 antibody, zinc finger protein 106 homolog (mouse) antibody, zinc finger protein 106 L homeolog antibody, ZNF106 antibody, ZFP106 antibody, znf106.L antibody, znf106 antibody, Zfp106 antibody

Background: Background: Zinc finger protein homolog 106 (ZFP106) is a C2H2-type zinc finger protein that also contains 2 WD repeats. ZFP106 is highly expressed in striated muscle, brown fat, and developing brain and is regulated by myogenin and nuclear respiratory factor-1 (NRF-1). ZFP106 localizes to the nucleus in association with nucleolar transcriptional machinery. The WD40 repeat in ZFP106 appears to facilitate targeting of ZFP106 to the nucleolus and to mediate the interaction between ZFP106 and testis-specific gene 118 (TSF118). A two-hybrid screen has identified testis-specific Y-encoded-like protein (TSPYL) as a ZFP106 interacting protein. These data suggest an important role for ZFP106 in testis development.

Gene ID: 64397

NCBI Accession: NP_071918

UniProt: Q9H2Y7