HMGN3 antibody (AA 30-60)

Catalog No. ABIN7454391

Product Details anti-HMGN3 Antibody

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Binding Specificity: AA 30-60

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGN3 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-HMGN3 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: between AA 30 and 60

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: Not recommended. Use rabbit anti-HMGN3 antibody A301-192A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for HMGN3

Target: HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))

Alternative Name: HMGN3 (HMGN3 Products)

Synonyms: Trip7 antibody, PNAS-25 antibody, TRIP7 antibody, 1110002A15Rik antibody, 6330514M13Rik antibody, BB071015 antibody, high mobility group nucleosomal binding domain 3 L homeolog antibody, high mobility group nucleosomal binding domain 3 antibody, hmgn3.L antibody, HMGN3 antibody, Hmgn3 antibody

Background: Background: HMGN3 was originally identified in a screen for interaction partners of the thyroid hormone receptor. HMGN3 belongs to the HMGN family of small basic proteins that interacts specifically with nucleosomes and functions to facilitate chromatin unfolding to allow access of transcription factors to DNA targets. HMGN has been found to be a regulator of the glycine transporter 1 (GLYT1) gene.

Gene ID: 9324

NCBI Accession: NP_004233

UniProt: Q15651