PELP1 antibody (AA 25-75)
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- Target See all PELP1 Antibodies
- PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))
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Binding Specificity
- AA 25-75
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PELP1 antibody is un-conjugated
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Application
- Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Purpose
- Rabbit anti-PELP1/MNAR Antibody, Affinity Purified
- Predicted Reactivity
- Monkey
- Purification
- Affinity Purified
- Immunogen
- between AA 25 and 75
- Isotype
- IgG
- Top Product
- Discover our top product PELP1 Primary Antibody
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- Application Notes
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-PELP1/MNAR antibody A300-180A.
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))
- Alternative Name
- PELP1/MNAR (PELP1 Products)
- Synonyms
- MNAR antibody, P160 antibody, RGD1306320 antibody, 4930563C04Rik antibody, proline, glutamate and leucine rich protein 1 antibody, proline, glutamate and leucine rich protein 1 L homeolog antibody, proline, glutamic acid and leucine rich protein 1 antibody, PELP1 antibody, Pelp1 antibody, pelp1.L antibody
- Background
- Background: PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the ""signalsome"" involving ERalpha, Src kinase, PI3K, SHC, and G-proteins. As a transcriptional coregulator and signaling protein, PELP/MNAR mediates a variety of cellular functions such as cell proliferation, apoptosis, differentiation, oncogenesis and metastasis.
- Gene ID
- 27043
- UniProt
- Q8IZL8
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