KDM4A antibody (AA 350-400)
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- Target See all KDM4A Antibodies
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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Binding Specificity
- AA 350-400
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KDM4A antibody is un-conjugated
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Application
- Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Purpose
- Rabbit anti-JMJD2A Antibody, Affinity Purified
- Predicted Reactivity
- Orangutan
- Purification
- Affinity Purified
- Immunogen
- between AA 350 and 400
- Isotype
- IgG
- Top Product
- Discover our top product KDM4A Primary Antibody
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- Application Notes
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-JMJD2A antibody A300-861A.
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
- Alternative Name
- JMJD2A (KDM4A Products)
- Synonyms
- JMJD2A antibody, JHDM3A antibody, JMJD2 antibody, TDRD14A antibody, D4Ertd222e antibody, Jmjd2 antibody, Jmjd2a antibody, mKIAA0677 antibody, lysine demethylase 4A antibody, lysine-specific demethylase 4A antibody, lysine (K)-specific demethylase 4A antibody, KDM4A antibody, LOC100228023 antibody, Kdm4a antibody
- Background
- Background: JMJD2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2A is a trimethylation-specific demethylase and functions as a transcriptional repressor. JMJD2A interacts with pRb and class one histone deacetylases to mediate repression of E2F-regulated promoters.
- Gene ID
- 9682
- NCBI Accession
- NP_055478
- UniProt
- O75164
- Pathways
- Warburg Effect
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