DHX38 antibody (AA 1150-1200)

Catalog No. ABIN7454376

Product Details anti-DHX38 Antibody

Target: DHX38 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 38 (DHX38))

Binding Specificity: AA 1150-1200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX38 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-DHX38 Antibody, Affinity Purified

Predicted Reactivity: Bovine

Purification: Affinity Purified

Immunogen: between AA 1150 and 1200

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-DHX38 antibody A300-859A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DHX38

Target: DHX38 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 38 (DHX38))

Alternative Name: DHX38 (DHX38 Products)

Synonyms: zgc:63517 antibody, DHX38 antibody, DDX38 antibody, PRP16 antibody, PRPF16 antibody, 5730550P09Rik antibody, AI325984 antibody, AW540902 antibody, Ddx38 antibody, Prp16 antibody, mKIAA0224 antibody, DEAH (Asp-Glu-Ala-His) box polypeptide 38 antibody, DEAH-box helicase 38 antibody, pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 antibody, dhx38 antibody, DHX38 antibody, LOC100638345 antibody, Dhx38 antibody

Background: Background: DHX38 is a member of the DEAH box family of proteins that possesses several conserved motifs which include the highly conserved DEAH (Asp-Glu-Ala-His) amino acid sequence motif. The major activity of DEAH box proteins is to function as ATP-dependent RNA helicases. RNA helicases play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DHX38 is the human ortholog of the yeast Prp16 protein. DHX38 has been shown to be required for catalytic step II of pre-mRNA splicing.

Gene ID: 9785

NCBI Accession: NP_054722

UniProt: Q92620