PSIP1 antibody (AA 225-275)

Catalog No. ABIN7454375

Product Details anti-PSIP1 Antibody

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Binding Specificity: AA 225-275

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSIP1 antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-LEDGF/p75 Antibody, Affinity Purified

Predicted Reactivity: Cat

Purification: Affinity Purified

Immunogen: between AA 225 and 275

Isotype: IgG

Application Details

Application Notes:

IHC: 1:2,000 to 1:10,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-LEDGF antibody A300-848A.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PSIP1

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Alternative Name: LEDGF/p75 (PSIP1 Products)

Synonyms: PSIP1 antibody, im:7149861 antibody, zgc:109898 antibody, LEDGF antibody, p75 antibody, PSIP2 antibody, DFS70 antibody, PAIP antibody, p52 antibody, AA408851 antibody, AU015605 antibody, Dfs70 antibody, Ledgfa antibody, Ledgfb antibody, Psip2 antibody, Ledgf antibody, SBP75 antibody, LEDGF/p75 antibody, PC4 and SFRS1 interacting protein 1 S homeolog antibody, PC4 and SFRS1 interacting protein 1 antibody, PC4 and SFRS1 interacting protein 1a antibody, LEDGF/p75 transcription factor-like antibody, psip1.S antibody, PSIP1 antibody, psip1a antibody, psip1 antibody, Psip1 antibody

Background: Background: LEDGF/p75 has been identified as a transcriptional coactivator involved in lens epithelial cell gene regulation and in neuroepithelial stem cell differentiation and neurogenesis. LEDGF has also been shown to function as a cofactor for lentivirus and HIV integration.

Gene ID: 11168

NCBI Accession: NP_150091

UniProt: O75475

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization