NCOA5 antibody (C-Term)

Catalog No. ABIN7453864

Product Details anti-NCOA5 Antibody

Target: NCOA5 (Nuclear Receptor Coactivator 5 (NCOA5))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCOA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-NCOA5/CIA Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 525 and C-term

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NCOA5

Target: NCOA5 (Nuclear Receptor Coactivator 5 (NCOA5))

Alternative Name: NCOA5/CIA (NCOA5 Products)

Synonyms: cia antibody, MGC53979 antibody, MGC75993 antibody, zgc:92194 antibody, CIA antibody, bA465L10.6 antibody, nuclear receptor coactivator 5 L homeolog antibody, nuclear receptor coactivator 5 antibody, ncoa5.L antibody, ncoa5 antibody, NCOA5 antibody, Ncoa5 antibody

Background: Background: NCOA5 (Nuclear Receptor Coactivator 5), also known as CIA (Coactivator Independent of AF-2 function), has been shown interact exclusively with estrogen receptor alpha (ERalpha) and beta (ERbeta) to function as a coactivator and enhance transcriptional activation by ER. NCOA5 has also been demonstrated to function as a corepressor of MYC/c-myc in response to 17-beta estradiol.

Gene ID: 57727

NCBI Accession: NP_066018

UniProt: Q9HCD5