Spt6 antibody (AA 425-475)

Catalog No. ABIN7453850

Product Details anti-Spt6 Antibody

Target: Spt6 (SUPT6H) (Suppressor of Ty 6 Homolog (SUPT6H))

Binding Specificity: AA 425-475

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Spt6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-SUPT6H Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 425 and 475

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Spt6

Target: Spt6 (SUPT6H) (Suppressor of Ty 6 Homolog (SUPT6H))

Alternative Name: SUPT6H (SUPT6H Products)

Synonyms: SPT6 antibody, SPT6H antibody, emb-5 antibody, 5131400N11Rik antibody, AI132449 antibody, Supt6h antibody, mKIAA0162 antibody, Spt6 antibody, wu:fj42h11 antibody, SUPT6H antibody, spt6 antibody, spt6h antibody, MGC146884 antibody, SPT6 homolog, histone chaperone antibody, suppressor of Ty 6 antibody, SUPT6H,-like protein to suppressor of ty 6 antibody, transcription elongation factor SPT6 antibody, suppressor of Ty 6 homolog (S. cerevisiae) antibody, chromatin-remodeling histone chaperone antibody, SUPT6H antibody, Supt6 antibody, Supt6h antibody, supt6h antibody, LOC100092175 antibody, SPT6 antibody

Background: Background: Transcription elongation is one step in the multistage process of transcription that involves the polymerization of nucleoside monophosphates into a ribonucleotide transcript catalyzed by the multisubunit complex RNA Pol II. Transcriptional regulation involves positive factors that promote sufficient elongation rates and processivity as well as negative elongation factors that repress transcription elongation. SUPT6H is hypothesized to play a role in enhancing the rate of transcription elongation in association with RNA Pol II by mobilizing histones and modulating chromatin structure.

Gene ID: 6830

NCBI Accession: NP_003161

UniProt: Q7KZ85

Pathways: Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response