ORC3 antibody (AA 325-375)

Catalog No. ABIN7453837

Product Details anti-ORC3 Antibody

Target: ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))

Binding Specificity: AA 325-375

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-ORC3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 325 and 375

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ORC3

Target: ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))

Alternative Name: ORC3 (ORC3 Products)

Background: Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. ORC3 is also known as ORC3L and is a subunit of the human ORC complex. ORC3L forms a core complex with ORC2L, -4L, and -5L [taken from NCBI Entrez Gene (GeneID: 23595)].

Gene ID: 23595

NCBI Accession: NP_036513

UniProt: Q9UBD5

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Feeding Behaviour, Synthesis of DNA