Symplekin antibody (AA 1224-1274)

Catalog No. ABIN7453798

Product Details anti-Symplekin Antibody

Target: Symplekin (SYMPK)

Binding Specificity: AA 1224-1274

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Symplekin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-Symplekin Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1224 and 1274

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Symplekin

Target: Symplekin (SYMPK)

Alternative Name: Symplekin (SYMPK Products)

Synonyms: SPK antibody, SYM antibody, CG2097 antibody, Dmel\\CG2097 antibody, dSymp antibody, 1500016F02Rik antibody, 4632415H16Rik antibody, AA125406 antibody, AI449890 antibody, Hfn3g antibody, sympk antibody, MGC75595 antibody, SYMPK antibody, T22C5.3 antibody, DKFZp468C0711 antibody, symplekin antibody, Symplekin antibody, symplekin S homeolog antibody, SYMPK antibody, Sym antibody, Sympk antibody, sympk.S antibody, sympk antibody, LOC552752 antibody, AT1G27595 antibody, LOC5580150 antibody, CpipJ_CPIJ011126 antibody, Bm1_50390 antibody, NAEGRDRAFT_80124 antibody, LOAG_00841 antibody

Background: Background: Symplekin is a component of tight junctions that also localizes to the nucleus and is a component of 3'-end processing machinery. As part of the mRNA 3'-end processing machinery symplekin is necessary for poly(A) tail elongation. Although histone mRNA 3'ends are not polyadenylated, symplekin has been shown to also play a role in 3'end maturation of histone mRNAs.

Gene ID: 8189

NCBI Accession: NP_004810

UniProt: Q92797