MSK2 antibody (AA 722-772)
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- Target See all MSK2 (RPS6KA4) Antibodies
- MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))
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Binding Specificity
- AA 722-772
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MSK2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Purpose
- Rabbit anti-MSK2 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogen
- between AA 722 and 772
- Isotype
- IgG
- Top Product
- Discover our top product RPS6KA4 Primary Antibody
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- Application Notes
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))
- Alternative Name
- MSK2 (RPS6KA4 Products)
- Synonyms
- MSK2 antibody, RSK-B antibody, 1110069D02Rik antibody, 90kDa antibody, AI848992 antibody, Msk2 antibody, mMSK2 antibody, ribosomal protein S6 kinase A4 antibody, ribosomal protein S6 kinase, polypeptide 4 antibody, RPS6KA4 antibody, Rps6ka4 antibody
- Background
- Background: MSK1 is a serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). MSK1 Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. MSK1 also phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. [taken from the Universal Protein Resource (UniProt) O75582].
- Gene ID
- 8986
- NCBI Accession
- NP_003933
- UniProt
- O75676
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