DDX54 antibody (AA 625-675)

Catalog No. ABIN7453689

Product Details anti-DDX54 Antibody

Target: DDX54 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 54 (DDX54))

Binding Specificity: AA 625-675

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX54 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-DDX54 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 625 and 675

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DDX54

Target: DDX54 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 54 (DDX54))

Alternative Name: DDX54 (DDX54 Products)

Synonyms: DDX54 antibody, DP97 antibody, chunp6913 antibody, mgc2835 antibody, zgc:111908 antibody, 2410015A15Rik antibody, AI414901 antibody, RGD1562539 antibody, DEAD-box helicase 54 antibody, DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 antibody, DEAD-box helicase 54 L homeolog antibody, DDX54 antibody, ddx54 antibody, ddx54.L antibody, Ddx54 antibody

Background: Background: DDX54 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. DDX54 has been shown to interact with nuclear hormone receptors in a hormone -dependent manner and repress their transcriptional activity.

Gene ID: 79039

NCBI Accession: NP_076977

UniProt: Q8TDD1

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway