MAD2 antibody (AA 100-150)
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- Target See all MAD2 products
- MAD2
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Binding Specificity
- AA 100-150
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAD2 antibody is un-conjugated
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Application
- Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Purpose
- Rabbit anti-MAD2 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogen
- between AA 100 and 150
- Isotype
- IgG
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- Application Notes
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IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-MAD2 antibody ABIN7450431.
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- MAD2
- Abstract
- MAD2 Products
- Synonyms
- AA673185 antibody, MAD2 antibody, MXD2 antibody, MXI antibody, bHLHc11 antibody, MAD2 mitotic arrest deficient-like 1 antibody, MAD2 mitotic arrest deficient-like 1 (yeast) antibody, MAX interactor 1, dimerization protein antibody, Mad2l1 antibody, MAD2L1 antibody, MXI1 antibody
- Background
- Background: MAD2 (Mitotic Arrest Deficiency 2) is a component of the mitotic spindle-assembly checkpoint that ensures that all chromosomes are aligned at the metaphase plate before the onset of anaphase. MAD2 is a subunit of the MCC complex that includes BubR1, Bub3, Cdc20 and Mad2, which may function to inhibit the APC/c (Anaphase Promoting Complex/Cyclosome). MAD2 is regulated by MAD1.
- Gene ID
- 4085
- NCBI Accession
- NP_002349
- UniProt
- Q13257
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