Importin 4 antibody (AA 350-400)
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- Target See all Importin 4 (IPO4) Antibodies
- Importin 4 (IPO4)
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Binding Specificity
- AA 350-400
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Importin 4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Purpose
- Rabbit anti-Importin 4 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogen
- between AA 350 and 400
- Isotype
- IgG
- Top Product
- Discover our top product IPO4 Primary Antibody
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- Application Notes
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 5 - 15 μg/mg lysate
WB: Not recommended. ABIN7453529 has not performed satisfactorily when used for WB of Importin 4 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Importin 4.
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- Importin 4 (IPO4)
- Alternative Name
- Importin 4 (IPO4 Products)
- Synonyms
- Imp4 antibody, 8430408O15Rik antibody, AA409693 antibody, Imp4a antibody, RanBP4 antibody, importin 4 antibody, IPO4 antibody, Ipo4 antibody
- Background
- Background: Importin 4 mediates the nuclear import of RPS3A. In vitro, it mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. Additionally, along with importin 7, importin 4 has been shown to be involved in nuclear import of HIF-1alpha [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q8TEX9].
- Gene ID
- 79711
- NCBI Accession
- NP_078934
- UniProt
- Q8TEX9
- Pathways
- Protein targeting to Nucleus
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