NCBP2 antibody (AA 106-156)

Catalog No. ABIN7453528

Product Details anti-NCBP2 Antibody

Target: NCBP2 (Nuclear Cap Binding Protein Subunit 2 (NCBP2))

Binding Specificity: AA 106-156

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCBP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-NCBP2 Antibody, Affinity Purified

Predicted Reactivity: Bovine

Purification: Affinity Purified

Immunogen: between AA 106 and 156

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 5 - 15 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NCBP2

Target: NCBP2 (Nuclear Cap Binding Protein Subunit 2 (NCBP2))

Alternative Name: NCBP2 (NCBP2 Products)

Synonyms: CBP20 antibody, CG12357 antibody, Dmel\\CG12357 antibody, 20kDa antibody, 5930413E18Rik antibody, AA536802 antibody, AI843301 antibody, C79367 antibody, CHUNP6917 antibody, zgc:92592 antibody, CBC2 antibody, NIP1 antibody, ATCBP20 antibody, CAP-binding protein 20 antibody, MLN1.12 antibody, MLN1_12 antibody, Ncbp2 antibody, cap binding protein 20 antibody, nuclear cap binding protein subunit 2 antibody, nuclear cap binding protein subunit 2, 20kDa antibody, nuclear cap binding protein subunit 2 L homeolog antibody, nuclear cap-binding protein subunit 2 antibody, CAP-binding protein 20 antibody, Nuclear cap-binding protein subunit 2 antibody, Cbp20 antibody, Ncbp2 antibody, ncbp2 antibody, NCBP2 antibody, ncbp2.L antibody, CBP20 antibody, ncbp-2 antibody

Background: Background: Nuclear cap binding protein subunit 2 (NCBP2) is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. NCBP2 has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay [taken from NCBI Entrez Gene (GeneID: 22916)].

Gene ID: 22916

NCBI Accession: NP_031388

UniProt: P52298

Pathways: Ribonucleoprotein Complex Subunit Organization, Methionine Biosynthetic Process