L3MBTL2 antibody (AA 655-705)

Catalog No. ABIN7453517

Product Details anti-L3MBTL2 Antibody

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Binding Specificity: AA 655-705

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L3MBTL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-L3MBTL2 Antibody, Affinity Purified

Predicted Reactivity: Bovine,Orangutan

Purification: Affinity Purified

Immunogen: between AA 655 and 705

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for L3MBTL2

Target: L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

Alternative Name: L3MBTL2 (L3MBTL2 Products)

Synonyms: L3MBTL2 antibody, im:7137244 antibody, wu:fb04e09 antibody, zgc:66491 antibody, H-l(3)mbt-l antibody, L3MBT antibody, 4732493N06Rik antibody, M4mbt antibody, L3MBTL2 polycomb repressive complex 1 subunit antibody, L3MBTL2, polycomb repressive complex 1 subunit antibody, l(3)mbt-like 2 (Drosophila) antibody, L3MBTL2 antibody, l3mbtl2 antibody, L3mbtl2 antibody

Background: Background: Lethal (3) malignant brain tumor-like protein 2 (L3MBTL2) is a putative polycomb group (PcG) protein. Its association with a chromatin-remodeling complex suggests that it may contribute to the repression of genes that trigger the cell into mitosis. L3MBTL2 binds to monomethylated and dimethylated 'Lys-20' on histone H4. It also binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' [taken from the Universal Protein Resource (UniProt) Q969R5].

Gene ID: 83746

NCBI Accession: NP_113676

UniProt: Q969R5