NPAT antibody (AA 700-750)

Catalog No. ABIN7453506

Product Details anti-NPAT Antibody

Target: NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))

Binding Specificity: AA 700-750

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPAT antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-NPAT Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 700 and 750

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended. Use rabbit anti-NPAT antibody ABIN7453485.

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for NPAT

Target: NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))

Alternative Name: NPAT (NPAT Products)

Background: Background: NPAT (nuclear protein of the ataxia telangiectasia mutated locus) is required for progression through the G1 and S phases of the cell cycle and for S phase entry. It activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. NPAT also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14207].

Gene ID: 4863

NCBI Accession: NP_002510

UniProt: Q14207