TCEB2 antibody (AA 68-118)
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- Target See all TCEB2 Antibodies
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
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Binding Specificity
- AA 68-118
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TCEB2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Purpose
- Rabbit anti-TCEB2 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogen
- Between AA 68 and 118
- Isotype
- IgG
- Top Product
- Discover our top product TCEB2 Primary Antibody
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- Application Notes
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:500 - 1:2,500
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))
- Alternative Name
- TCEB2 (TCEB2 Products)
- Synonyms
- 0610040H15Rik antibody, cb162 antibody, wu:fb47e08 antibody, ELOB antibody, SIII antibody, elongin B antibody, Elob antibody, elob antibody, ELOB antibody
- Background
- Background: TCEB2, also known as Elongin B, is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation [taken from NCBI Entrez Gene (Gene ID: 6923)].
- Gene ID
- 6923
- NCBI Accession
- NP_009039
- UniProt
- Q15370
- Pathways
- SARS-CoV-2 Protein Interactome
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