Indian Hedgehog antibody (AA 161-260)

Catalog No. ABIN719021

Product Details anti-Indian Hedgehog Antibody

Target: Indian Hedgehog (IHH)

Binding Specificity: AA 161-260

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Indian Hedgehog antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IHH

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Indian Hedgehog

Target: Indian Hedgehog (IHH)

Alternative Name: IHH (IHH Products)

Synonyms: BDA1 antibody, HHG2 antibody, X-hh antibody, Xbhh antibody, bhh antibody, bhh-a antibody, IHH antibody, ehh antibody, zgc:113262 antibody, indian hedgehog antibody, Indian hedgehog antibody, indian hedgehog S homeolog antibody, Indian hedgehog homolog b antibody, IHH antibody, Ihh antibody, ihh.S antibody, ihhb antibody

Background:

Synonyms: HHG2, Indian Hedgehog, CENPB_HUMAN, Major centromere autoantigen B, Centromere protein B, CENP-B.

Background: Ihh is an intercellular signalling peptide essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Ihh induces the expression of parathyroid hormone-related protein (PTHRP) and is implicated in endochondral ossification, possibly regulating the balance between growth and ossification of the developing bones.

Gene ID: 3549

Pathways: Hedgehog Signaling