SMC2 antibody (C-Term)

Catalog No. ABIN7453335

Product Details anti-SMC2 Antibody

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Rabbit anti-SMC2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1150 and C-term

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

ICC: 1:200 - 1:400

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SMC2

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Alternative Name: SMC2 (SMC2 Products)

Synonyms: CAP-E antibody, CAPE antibody, SMC-2 antibody, SMC2L1 antibody, 5730502P04Rik antibody, AI255214 antibody, AW545314 antibody, Fin16 antibody, Smc2l1 antibody, fb92e05 antibody, wu:fb92e05 antibody, zeh1628 antibody, zgc:55326 antibody, xcap-e antibody, SCII antibody, structural maintenance of chromosomes 2 antibody, structural maintenance of chromosomes 2 L homeolog antibody, SMC2 antibody, Smc2 antibody, smc2 antibody, smc2.L antibody

Background: Background: Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core condensin complex includes a heterodimer of SMC2 and SMC4 that functions to create positively supercoiled loops for chromatin condensation and metaphase chromatid shaping. A function for condensin in the DNA damage checkpoint response and gene repression has also been suggested.

Gene ID: 10592

NCBI Accession: NP_006435

UniProt: O95347