SRP72 antibody (AA 621-671)

Catalog No. ABIN7453212

Product Details anti-SRP72 Antibody

Target: SRP72 (Signal Recognition Particle 72kDa (SRP72))

Binding Specificity: AA 621-671

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRP72 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit anti-SRP72 Antibody, Affinity Purified

Predicted Reactivity: Dog

Purification: Affinity Purified

Immunogen: Between AA 621 and 671

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SRP72

Target: SRP72 (Signal Recognition Particle 72kDa (SRP72))

Alternative Name: SRP72 (SRP72 Products)

Background: Background: Signal recognition particle subunit SRP72 is the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure [taken from NCBI Entrez Gene (Gene ID: 6731)].

Gene ID: 6731

NCBI Accession: NP_008878

UniProt: O76094

Pathways: SARS-CoV-2 Protein Interactome