PTRH2 antibody (AA 129-179)
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- Target See all PTRH2 Antibodies
- PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))
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Binding Specificity
- AA 129-179
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTRH2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit anti-PTRH2/BIT1 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogen
- Between AA 129 and 179
- Isotype
- IgG
- Top Product
- Discover our top product PTRH2 Primary Antibody
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- Application Notes
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IP: Not recommended
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
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- Concentration
- 1000 μg/mL
- Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- PTRH2 (Peptidyl-tRNA Hydrolase 2 (PTRH2))
- Alternative Name
- PTRH2/BIT1 (PTRH2 Products)
- Synonyms
- BIT1 antibody, PTH2 antibody, A230072I16Rik antibody, Bit1 antibody, CGI-147 antibody, wu:fj09f02 antibody, zgc:109954 antibody, RGD1306819 antibody, peptidyl-tRNA hydrolase 2 antibody, ptrh2 antibody, CC1G_10259 antibody, ANI_1_1036184 antibody, AOR_1_2082154 antibody, PTRH2 antibody, Ptrh2 antibody
- Background
- Background: Peptidyl-tRNA hydrolase 2 (PTRH2) is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos [taken from NCBI Entrez Gene (Gene ID: 51651)].
- Gene ID
- 51651
- UniProt
- Q9Y3E5
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